Let’s get started
By clicking ‘Next’, I agree to the Terms of Service
and Privacy Policy, and consent to receive emails from Rise
Jobs / Job page
Principal Software Engineer image - Rise Careers
Job details

Principal Software Engineer

Department

BSD CTD - Engineering - Plan X


About the Department

The Center for Translational Data Science (CTDS) at the University of Chicago is a research center whose mission is to develop the discipline of translational data science to impactful problems in biology, medicine, healthcare, and the environment. We envision a world in which researchers have ready access to the data needed and the tools required to make data driven discoveries that increase our scientific knowledge and improve the quality of life. We architect ecosystems of large-scale commons of research data, computing resources, applications, tools, and services for the broader research community to use data at scale to pursue scientific inquiry and accelerate discovery. Learn more at https://gdc.cancer.gov/, https://gen3.org/, https://stats.gen3.org/, and https://ctds.uchicago.edu/.


Job Summary

The job leads and provides expertise to the development of programs for activities relating to software support and/or development. Analyzes, designs, develops, debugs, and modifies computer code for end user applications, beta general releases, and production support. Manages development and implementation of applications, web pages, and user-interfaces using a variety of software applications, techniques, and tools. Solves complex problems in administration, maintenance, integration, and troubleshooting of code and application ecosystem currently in production.

The Principal Software Engineer is responsible for a scope of significant size or functional area critical to the team’s success, using in-depth knowledge in all technical areas of major projects and core product and responsible for design and implementation of top priority technical tasks, timely and quality delivery, leading and mentoring other engineers, and helping the organization drive toward its strategic goals, negotiating complex solutions along the way. All Software Engineers perform web application development activities of open-source software platforms, including analyzing business and technical requirements, designing/developing/testing software, reviewing and testing code, supporting and maintaining applications, and providing appropriate written documentation of project development and programming code. All engineers are expected to be flexible for full-stack development and some may have a specialty in back-end or front-end technologies.

This at-will position is wholly or partially funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.

Responsibilities

  • Responsible for design and implementation of top priority technical tasks and timely delivery of such tasks, meeting and defining the required level of quality.

  • Participation in complex and challenging activities, including design and implementation.

  • Responsible for managing activities of a complex and challenging nature, including design and implementation of large systems and/or core components.

  • Provide technical leadership and effectively mentor staff.

  • Actively participate in and define the hiring process and provide fair and productive interview feedback.

  • Negotiate complex decisions, present options, and persuasively advocate for optimal technical solutions, internally and externally.

  • Leads in the development of new systems, features, and tools. Solves complex problems and identifies opportunities for technical improvement and performance optimization. Reviews and tests code to ensure appropriate standards are met.

  • Utilizes in-depth technical knowledge of existing and emerging technologies, including public cloud offerings from Amazon Web Services, Microsoft Azure, and Google Cloud.

  • Acts as a technical consultant and resource for faculty research, teaching, and/or administrative projects.

  • Leads or coordinates teams or projects for activities relating to software support and/or development.

  • Performs other related work as needed.


Minimum Qualifications

Education:

Minimum requirements include a college or university degree in related field.


Work Experience:

Minimum requirements include knowledge and skills developed through 7+ years of work experience in a related job discipline.


Certifications:

---

Preferred Qualifications

Education:

  • Advanced degree in computer science, mathematics, statistics, engineering, or a relevant quantitative field strongly preferred.

Experience:

  • 9+ years of relevant software development experience, full cycle strongly preferred, including design, coding, testing, and support. 

  • ​Advanced programming skills, especially in Python, Golang, and Typescript. Other languages such as C++, Java, or C# may be helpful. 

  • Knowledge of web applications, REST API, microservices, and containers. 

  • Knowledge of Elasticsearch, PostgreSQL, Spark, Hadoop, and data analysis. 

  • Knowledge of infrastructure-as-code tools (Terraform, Helm) and container orchestration platforms (Kubernetes).

  • High performance/cloud computing experience (AWS, GCP, Azure, Openstack). 

  • ​Unix/Linux programming, open source, and version control experience. 

  • Experience with CI/CD and Agile methodologies​.

Preferred Competencies 

  • Ability to work productively with all stakeholders and drive best practices, ensuring accountability for deliverables and outcomes.

  • Ability to take a broad plan and break it into incremental tasks, estimate the effort needed to complete them, and ensure the completion of each task, meeting the required level of quality.

  • Ability to prioritize and manage workload to meet critical project milestones and deadlines.

  • Ability to plan and persuade others to adopt new structures or systems in order to meet objectives.

  • Ability to take and provide constructive and helpful input and feedback on technical issues.

  • In-depth knowledge in all technical areas of major projects and the core product.

  • Considered a Subject Matter Expert of all technology, programming languages, and core solutions.

Working Conditions

  • Office Environment.

Application Documents

  • Resume (required)

  • Cover Letter (preferred)


When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.


Job Family

Information Technology


Role Impact

Individual Contributor


Scheduled Weekly Hours

40


Drug Test Required

No


Health Screen Required

No


Motor Vehicle Record Inquiry Required

No


Pay Rate Type

Salary


FLSA Status

Exempt


Pay Range

$120,000.00 - $170,000.00

The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.


Benefits Eligible

Yes

The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.


Posting Statement

The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

 

Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

 

All offers of employment are contingent upon a background check that includes a review of conviction history.  A conviction does not automatically preclude University employment.  Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

 

The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

Average salary estimate

$145000 / YEARLY (est.)
min
max
$120000K
$170000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

Similar Jobs
Photo of the Rise User
Inclusive & Diverse
Empathetic
Take Risks
Transparent & Candid
Feedback Forward
Mission Driven
Collaboration over Competition
Work/Life Harmony
Maternity Leave
Paternity Leave
Snacks
Medical Insurance
Dental Insurance
Vision Insurance
Mental Health Resources
Life insurance
401K Matching
Paid Sick Days
Paid Time-Off
Paid Volunteer Time

Lead the architecture and productionization of Spotify’s shared Agent Engine to power scalable, reliable agent-based experiences across the platform.

Photo of the Rise User

GR0 is hiring an on-site Applied AI Engineering Intern in Marina Del Rey to design and ship production-grade AI prototypes that improve marketing speed, quality, and performance.

Photo of the Rise User
Pinterest Hybrid San Francisco, CA, US; Palo Alto, CA, US
Posted 2 hours ago

Lead cross-team engineering to build scalable catalog, integration, and AI-native merchant systems that improve onboarding, catalog health, and merchant growth at Pinterest.

Photo of the Rise User

Make infrastructure resilient and scalable at Visa by building automation, database reliability tooling, and GenAI-powered engineering assistants on the Product Reliability Engineering team in Austin.

Photo of the Rise User
Posted 20 hours ago

CapTech is hiring a senior Full-Stack Developer (.NET) in Salt Lake City to deliver cloud-ready, API-driven enterprise applications and integrations across front-end and back-end stacks.

Photo of the Rise User

Work remotely on cloud infrastructure and data systems that power large-scale AI-driven automation for a mission-focused company transforming global waste systems.

Photo of the Rise User
PayPal Hybrid San Jose, California, United States of America
Posted 17 hours ago

Experienced backend-focused Staff Software Engineer needed to lead architecture and delivery of scalable Node.js/React services for PayPal's commerce platform.

Photo of the Rise User
NBCUniversal Hybrid 30 Rockefeller Plaza, New York, NEW YORK
Posted 12 hours ago

Senior Software Engineer needed to develop scalable, LLM-powered agentic systems and cloud-native backends for NBCUniversal's AI initiatives.

thomsonreuters Hybrid United States of America, Eagan, Minnesota
Posted 2 hours ago

Experienced software engineer needed to build and maintain cloud-based, customer-facing legal software using Java, JavaScript frameworks (e.g., Angular), and AWS in a hybrid Agile team environment.

Posted 14 hours ago

Temporal is hiring a Staff Software Engineer to lead the architecture and operation of internal builder tools and AI-driven agent platforms that improve developer flow and reliability across the organization.

Photo of the Rise User
Parloa Hybrid Remotely in the USA
Posted 16 hours ago

Design and build AI‑enabled internal systems and integrations to scale Parloa’s Go‑To‑Market operations using TypeScript, Python, and modern AI tooling.

Photo of the Rise User

Lead the architecture and implementation of LinkedIn’s network access control platform to automate secure, policy-driven connectivity across cloud and on‑prem production environments.

Photo of the Rise User
AVEVA Hybrid San Leandro, California, United States of America
Posted 14 hours ago

AVEVA is hiring a Distinguished AI Tech Lead to shape and operationalize frontier AI capabilities across industrial products, bridging advanced research and production delivery.

MATCH
Calculating your matching score...
FUNDING
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
No info
HQ LOCATION
No info
EMPLOYMENT TYPE
Full-time, onsite
DATE POSTED
March 30, 2026
Risa star 🔮 Hi, I'm Risa! Your AI
Career Copilot
Want to see a list of jobs tailored to
you, just ask me below!